The utilization of minimally invasive procedures has increased. A growing number of practitioners including radiologists, surgeons, and endoscopists have adopted minimally invasive procedures in their clinical practice. Multiple factors have contributed to the development of minimally invasive procedures, including advancements in medical imaging, which have enabled pioneers to begin performing precise procedures under image-guidance. In this lecture Prof. Giménez talks about advancements in medical imaging and image-guided Surgery.